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| {{enzyme
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| | Name = 3,7-dimethylquercitin 4'-O-methyltransferase
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| | EC_number = 2.1.1.83
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| | CAS_number = 96477-60-0
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| | IUBMB_EC_number = 2/1/1/83
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| | GO_code = 0030758
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| In [[enzymology]], a '''3,7-dimethylquercetin 4'-O-methyltransferase''' ({{EC number|2.1.1.83}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :S-adenosyl-L-methionine + 5,3',4'-trihydroxy-3,7-dimethoxyflavone <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + 5,3'-dihydroxy-3,7,4'-trimethoxyflavone | |
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[5,3',4'-trihydroxy-3,7-dimethoxyflavone]] (rhamnazin), whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[5,3'-dihydroxy-3,7,4'-trimethoxyflavone]] (ayanin).
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| This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is '''S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase'''. Other names in common use include '''flavonol 4'-O-methyltransferase''', '''flavonol 4'-methyltransferase''', '''4'-OMT''', '''S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone''', '''4'-O-methyltransferase''', and '''3,7-dimethylquercitin 4'-O-methyltransferase [mis-spelt]'''.
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| ==References== | |
| {{reflist|1}}
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| * {{cite journal | author = De Luca V, Ibrahim RK | date = 1985 | title = Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases | journal = Arch. Biochem. Biophys. | volume = 238 | pages = 596–605 | pmid = 3994393 | doi = 10.1016/0003-9861(85)90205-X | issue = 2 }}
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| * {{cite journal | author = De Luca V, Ibrahim RK | date = 1985 | title = Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4'-O-methyltransferases | journal = Arch. Biochem. Biophys. | volume = 238 | pages = 606–18 | pmid = 3994394 | doi = 10.1016/0003-9861(85)90206-1 | issue = 2 }}
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| {{transferase-stub}}
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| [[Category:EC 2.1.1]]
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| [[Category:Enzymes of unknown structure]]
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