Phenol O-methyltransferase: Difference between revisions

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m clean up using AWB
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m References: Added 1 doi to a journal cite using AWB (10213)
 
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{{enzyme
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| Name = precorrin-6A synthase (deacetylating)
| EC_number = 2.1.1.152
| CAS_number =
| IUBMB_EC_number = 2/1/1/152
| GO_code = 0043819
| image =
| width =
| caption =
}}
In [[enzymology]], a '''precorrin-6A synthase (deacetylating)''' ({{EC number|2.1.1.152}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:S-adenosyl-L-methionine + precorrin-5 + H<sub>2</sub>O <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + precorrin-6A + acetate
 
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]], [[precorrin 5]], and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[S-adenosylhomocysteine]], [[precorrin 6A]], and [[acetate]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases.  The systematic name of this enzyme class is '''S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating)'''. Other names in common use include '''precorrin-6X synthase (deacetylating)''', and '''CobF'''.  This enzyme participates in [[porphyrin and chlorophyll metabolism]]. 
 
==References==
{{reflist|1}}
* {{cite journal | author = Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F | date = 1993 | title = Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans | journal = J. Bacteriol.  | volume = 175 | pages = 7430&ndash;40  | pmid = 8226690 | issue = 22 | pmc = 206888 }}
* {{cite journal | author = Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC | date = 2002 | title = The biosynthesis of adenosylcobalamin (vitamin B12) | journal = Nat. Prod. Rep.  | volume = 19 | pages = 390&ndash;412  | pmid = 12195810 | doi = 10.1039/b108967f | issue = 4 }}
 
{{transferase-stub}}
 
[[Category:EC 2.1.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 12:01, 26 May 2014

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