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| {{enzyme
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| | Name = citrullinase
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| | EC_number = 3.5.1.20
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| | CAS_number = 59088-17-4
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| | IUBMB_EC_number = 3/5/1/20
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| | GO_code = 0047781
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| In [[enzymology]], a '''citrullinase''' ({{EC number|3.5.1.20}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :L-citrulline + H<sub>2</sub>O <math>\rightleftharpoons</math> L-ornithine + CO<sub>2</sub> + NH<sub>3</sub> | |
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[L-citrulline]] and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[L-ornithine]], [[carbon dioxide|CO<sub>2</sub>]], and [[ammonia|NH<sub>3</sub>]].
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| This enzyme belongs to the family of [[hydrolase]]s, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is '''L-citrulline N5-carbamoyldihydrolase'''. Other names in common use include '''citrulline ureidase''', '''citrulline hydrolase''', and '''L-citrulline 5-N-carbamoyldihydrolase'''.
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Hill DL, Chambers P | date = 1967 | title = The biosynthesis of proline by Tetrahymena pyriformis | journal = Biochim. Biophys. Acta. | volume = 148 | pages = 435–47 | pmid = 6075416 | issue = 2 }}
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| {{hydrolase-stub}}
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| [[Category:Hydrolases acting on nonpeptide C-N bonds]]
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| [[Category:Enzymes of unknown structure]]
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Latest revision as of 09:20, 16 December 2014
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