Lysine—pyruvate 6-transaminase: Difference between revisions

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{{enzyme
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| Name = (S)-3-amino-2-methylpropionate transaminase
| EC_number = 2.6.1.22
| CAS_number = 9031-95-2
| IUBMB_EC_number = 2/6/1/22
| GO_code = 0047298
| image =
| width =
| caption =
}}
In [[enzymology]], a '''(S)-3-amino-2-methylpropionate transaminase''' ({{EC number|2.6.1.22}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:(S)-3-amino-2-methylpropanoate + 2-oxoglutarate <math>\rightleftharpoons</math> 2-methyl-3-oxopropanoate + L-glutamate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[(S)-3-amino-2-methylpropanoate]] and [[2-oxoglutarate]], whereas its two [[product (chemistry)|products]] are [[2-methyl-3-oxopropanoate]] and [[L-glutamate]].
 
This enzyme belongs to the family of [[transferase]]s, specifically the [[transaminases]], which transfer nitrogenous groups.  The systematic name of this enzyme class is '''(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase'''. Other names in common use include '''L-3-aminoisobutyrate transaminase''', '''beta-aminobutyric transaminase''', '''L-3-aminoisobutyric aminotransferase''', and '''beta-aminoisobutyrate-alpha-ketoglutarate transaminase'''. This enzyme participates in [[valine, leucine and isoleucine degradation]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Kakimoto Y, Kanazawa A, Taniguchi K, Sano I | date = 1968 | title = Beta-aminoisobutyrate-alpha-ketoglutarate transaminase in relation to beta-aminoisobutyric aciduria | journal = Biochim. Biophys. Acta. | volume = 156 | pages = 374&ndash;80  | pmid = 5641913 | issue = 2 }}
* {{cite journal | author = Tamaki N, Sakata SF, Matsuda K | date = 2000 | title = Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver | journal = Methods Enzymol. | volume = 324 | pages = 376&ndash;89  | pmid = 10989446 | doi = 10.1016/S0076-6879(00)24247-X | series = Methods in Enzymology | isbn = 978-0-12-182225-5 }}
 
[[Category:EC 2.6.1]]
[[Category:Enzymes of unknown structure]]
 
{{transferase-stub}}

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