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In [[statistics]], a '''likelihood function''' (often simply the '''likelihood''') is a function of the [[statistical parameter|parameters]] of a [[statistical model]]. The ''likelihood'' of a set of parameter values, θ, given outcomes x, is equal to the ''probability'' of those observed outcomes given those parameter values, that is <math>\mathcal{L}(\theta |x) = P(x | \theta)</math>.
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Likelihood functions play a key role in [[statistical inference]], especially methods of estimating a parameter from a set of [[statistic]]s. In informal contexts, "likelihood" is often used as a synonym for "[[probability]]." But in statistical usage, a distinction is made depending on the roles of the outcome or parameter. ''Probability'' is used when describing a function of the outcome given a fixed parameter value. For example, if a coin is flipped 10 times and it is a fair coin, what is the ''probability'' of it landing heads-up every time? ''Likelihood'' is used when describing a function of a parameter given an ''outcome.'' For example, if a coin is flipped 10 times and it has landed heads-up 10 times, what is the ''likelihood'' that the coin is fair?
 
==Definition==
The likelihood function is defined differently for discrete and continuous probability distributions.
 
===Discrete probability distribution===
Let ''X'' be a random variable with a discrete probability distribution ''p'' depending on a parameter ''θ''. Then the function
 
:<math>\mathcal{L}(\theta |x) = p_\theta (x) = P_\theta (X=x), \, </math>
 
considered as a function of ''θ'', is called the likelihood function (of ''θ'', given the outcome ''x'' of ''X''). Sometimes the probability on the value ''x'' of ''X'' for the parameter value ''θ'' is written as <math>P(X=x|\theta)</math>; often written as <math>P(X=x;\theta)</math> to emphasize that this value is not a [[conditional probability]], because θ is a parameter and not a random variable.
 
===Continuous probability distribution===
Let ''X'' be a random variable with a continuous probability distribution with [[probability density function|density function]] ''f'' depending on a parameter ''θ''. Then the function
 
:<math>\mathcal{L}(\theta |x) = f_{\theta} (x), \, </math>
 
considered as a function of ''θ'', is called the likelihood function (of ''θ'', given the outcome ''x'' of ''X''). Sometimes the density function for the value ''x'' of ''X'' for the parameter value ''θ'' is written as <math>f(x|\theta)</math>, but should not be considered as a conditional probability density.
 
The actual value of a likelihood function bears no meaning. Its use lies in comparing one value with another. For example, one value of the parameter may be more likely than another, given the outcome of the sample. Or a specific value will be most likely: the maximum likelihood estimate. Comparison may also be performed in considering the quotient of two likelihood values. That is why <math>\mathcal{L}(\theta |x)</math> is generally permitted to be any positive multiple of the above defined function <math>\mathcal{L}</math>. More precisely, then, a likelihood function is any representative from an [[equivalence class]] of functions,
:<math>\mathcal{L} \in \left\lbrace \alpha \; P_\theta: \alpha > 0 \right\rbrace, \, </math>
where the constant of proportionality&nbsp;''α''&nbsp;>&nbsp;0 is not permitted to depend upon ''θ'', and is required to be the same for all likelihood functions used in any one comparison. In particular, the numerical value <math>\mathcal{L}</math>(''θ''&nbsp;|&nbsp;''x'') alone is immaterial; all that matters are maximum values of <math>\mathcal{L}</math>, or likelihood [[ratio]]s, such as those of the form
 
:<math>\frac{\mathcal{L}(\theta_2 | x)}{\mathcal{L}(\theta_1 | x)}
= \frac{\alpha P(X=x|\theta_2)}{\alpha P(X=x|\theta_1)}
= \frac{P(X=x|\theta_2)}{P(X=x|\theta_1)}, </math>
 
that are invariant with respect to the [[constant of proportionality]]&nbsp;''α''.
 
For more about making inferences via likelihood functions, see also the method of [[maximum likelihood]], and [[likelihood-ratio test]]ing.
 
==Log-likelihood==
For many applications involving likelihood functions, it is more convenient to work with the [[natural logarithm]] of the likelihood function, called the '''log-likelihood''', than it is to work with the likelihood function itself. Because the logarithm is a [[monotonically increasing]] function, the logarithm of a function achieves its [[maximum]] value at the same points as the function itself, and hence the log-likelihood can be used in place of the likelihood in [[maximum likelihood]] estimation and related techniques. Finding the maximum of a function often involves taking the [[derivative]] of a function and solving for the parameter being maximized, and this is often easier when the function being maximized is a log-likelihood rather than the original likelihood function.
 
For example, some likelihood functions are for the parameters that explain a collection of statistically independent observations. In such a situation, the likelihood function factors into a product of individual likelihood functions. The logarithm of this product is a sum of individual logarithms, and the [[derivative]] of a sum of terms is often easier to compute than the derivative of a product. In addition, several common distributions have likelihood functions that contain products of factors involving [[exponentiation]]. The logarithm of such a function is a sum of products, again easier to differentiate than the original function.
 
[[A. W. F. Edwards]] referred to the log-likelihood ratio as the '''support''', and the log-likelihood function as the '''support function'''.<ref>Edwards, A.W.F. 1972. ''Likelihood.'' Cambridge University Press, Cambridge (expanded edition, 1992, Johns Hopkins University Press, Baltimore). ISBN 0-8018-4443-6</ref> However, there is potential for confusion with the [[support (mathematics)|mathematical meaning of 'support']], and this terminology is not widely used outside Edwards' main applied field of [[phylogenetics]].
 
===Example: the gamma distribution===
 
As an example, consider the [[gamma distribution]], which has two parameters, ''α'' and ''β''. The likelihood function is
 
:<math>\mathcal{L} (\alpha, \beta \,|\, x) = \frac{\beta^\alpha}{\Gamma(\alpha)} x^{\alpha-1} e^{-\beta x}</math>.
 
Suppose we wish to find the maximum likelihood estimate of ''β'' for a single observed value ''x''. This function looks rather daunting. Its logarithm, however, is much simpler to work with:
 
:<math>\log \mathcal{L}(\alpha,\beta \,|\, x) = \alpha \log \beta - \log \Gamma(\alpha) + (\alpha-1) \log x  - \beta x. \, </math>
 
Maximizing the log-likelihood first requires taking the [[partial derivative]] with respect to ''β'':
 
:<math>\frac{\partial \log \mathcal{L}(\alpha,\beta \,|\, x)}{\partial \beta} = \frac{\alpha}{\beta} - x</math>.
 
If there are a number of independent random samples {{nowrap|''x''<sub>1</sub>, ..., ''x''<sub>''n''</sub>}}, then the joint log-likelihood will be the sum of individual log-likelihoods, and the derivative of this sum will be a sum of derivatives of each individual log-likelihood:
 
:<math>\frac{\partial \log \mathcal{L}(\alpha,\beta \,|\, x_1, \ldots, x_n)}{\partial \beta} = \frac{\partial \log \mathcal{L}(\alpha,\beta \,|\, x_1)}{\partial \beta} + \cdots + \frac{\partial \log \mathcal{L}(\alpha,\beta \,|\, x_n)}{\partial \beta} = \frac{n \alpha}{\beta} - \sum_{i=1}^n x_i.</math>
 
To complete the maximization procedure for the joint log-likelihood, the equation is set to zero and solved for ''β'':
 
:<math>\hat\beta = \frac{\alpha}{\bar{x}}.</math>
 
Here <math>\hat\beta</math> denotes the maximum-likelihood estimate, and <math>\bar{x} = \frac{1}{n} \sum_{i=1}^n x_i</math> is the [[sample mean]] of the observations.
 
==Likelihood function of a parameterized model==
Among many applications, we consider here one of broad theoretical and practical importance.  Given a [[parameterized family]] of [[probability density function]]s (or [[probability mass function]]s in the case of discrete distributions)
 
:<math>x\mapsto f(x\mid\theta), \!</math>
 
where ''θ'' is the parameter,  the '''likelihood function''' is
:<math>\theta\mapsto f(x\mid\theta), \!</math>
written
:<math>\mathcal{L}(\theta \mid x)=f(x\mid\theta), \!</math>
 
where ''x'' is the observed outcome of an experiment.  In other words, when ''f''(''x''&nbsp;|&nbsp;''θ'') is viewed as a function of ''x'' with ''θ'' fixed, it is a probability density function, and when viewed as a function of ''θ'' with ''x'' fixed, it is a likelihood function.
 
This is not the same as the probability that those parameters are the right ones, given the observed sample. Attempting to interpret the likelihood of a hypothesis given observed evidence as the probability of the hypothesis is a common error, with potentially disastrous consequences in medicine, engineering or jurisprudence. See [[prosecutor's fallacy]] for an example of this.
 
From a geometric standpoint, if we consider ''f'' (''x'',&nbsp;''θ'') as a function of two variables then the family of probability distributions can be viewed as a family of curves parallel to the ''x''-axis, while the family of likelihood functions are the orthogonal curves parallel to the ''θ''-axis.
 
===Likelihoods for continuous distributions===
The use of the [[probability density function|probability density]] instead of a probability in specifying the likelihood function above may be justified in a simple way. Suppose that, instead of an exact observation,&nbsp;''x'', the observation is the value in a short interval (''x''<sub>''j''&minus;1</sub>,&nbsp;''x''<sub>''j''</sub>), with length Δ<sub>''j''</sub>, where the subscripts refer to a predefined set of intervals. Then the probability of getting this observation (of being in interval&nbsp;''j'') is approximately
 
:<math>\mathcal{L}_\text{approx}(\theta \mid x \text{ in interval } j) = f(x_{*}\mid\theta) \Delta_j, \!</math>
 
where ''x''<sub>*</sub> can be any point in interval&nbsp;''j''. Then, recalling that the likelihood function is defined up to a multiplicative constant, it is just as valid to say that the likelihood function is approximately
 
:<math>\mathcal{L}_\text{approx}(\theta \mid x \text{ in interval } j)= f(x_{*}\mid\theta), \!</math>
 
and then, on considering the lengths of the intervals to decrease to zero,
 
:<math>\mathcal{L}(\theta \mid x )= f(x\mid\theta). \!</math>
 
===Likelihoods for mixed continuous&ndash;discrete distributions===
The above can be extended in a simple way to allow consideration of distributions which contain both discrete and continuous components. Suppose that the distribution consists of a number of discrete probability masses ''p<sub>k</sub>''(θ) and a density ''f''(''x''&nbsp;|&nbsp;''θ''), where the sum of all the ''p'''s added to the integral of ''f'' is always one. Assuming that it is possible to distinguish an observation corresponding to one of the discrete probability masses from one which corresponds to the density component, the likelihood function for an observation from the continuous component can be dealt with as above by setting the interval length short enough to exclude any of the discrete masses. For an observation from the discrete component, the probability can either be written down directly or treated within the above context by saying that the probability of getting an observation in an interval that does contain a discrete component (of being in interval&nbsp;''j'' which contains discrete component&nbsp;''k'') is approximately
 
:<math>\mathcal{L}_\text{approx}(\theta \mid x \text{ in interval } j \text{ containing discrete mass } k)=p_k(\theta) + f(x_{*}\mid\theta) \Delta_j, \!</math>
 
where <math>x_{*}\ </math> can be any point in interval&nbsp;''j''. Then, on considering the lengths of the intervals to decrease to zero, the likelihood function for an observation from the discrete component is
 
:<math>\mathcal{L}(\theta \mid x )= p_k(\theta), \!</math>
 
where ''k'' is the index of the discrete probability mass corresponding to observation&nbsp;''x''.
 
The fact that the likelihood function can be defined in a way that includes contributions that are not commensurate (the density and the probability mass) arises from the way in which the likelihood function is defined up to a constant of proportionality, where this "constant" can change with the observation&nbsp;''x'', but not with the parameter&nbsp;''θ''.
 
==Example 1==
[[Image:likelihoodFunctionAfterHH.png|thumb|400px|The likelihood function for estimating the probability of a coin landing heads-up without prior knowledge after observing HH]]
[[Image:likelihoodFunctionAfterHHT.png|thumb|400px|The likelihood function for estimating the probability of a coin landing heads-up without prior knowledge after observing HHT]]
Let <math>p_\text{H}</math> be the probability that a certain coin lands heads up (H) when tossed. So, the probability of getting two heads in two tosses (HH) is <math>p_\text{H}^2</math>. If <math>p_\text{H} = 0.5</math>, then the [[Conditional probability#Conditioning on a random variable|probability]] of seeing two heads is 0.25.
 
:<math>P(\text{HH} | p_\text{H}=0.5) = 0.25.</math>
 
Another way of saying this is that the likelihood that <math>p_\text{H} = 0.5</math>, given the observation HH, is 0.25, that is
 
:<math>\mathcal{L}(p_\text{H}=0.5 | \text{HH}) = P(\text{HH} | p_\text{H}=0.5) = 0.25.</math>
 
But this is not the same as saying that the probability that <math>p_\text{H} = 0.5</math>, given the observation HH, is 0.25. The likelihood that <math>p_\text{H} = 1</math>, given the observation HH, is 1, but it is not true that the probability that <math>p_\text{H} = 1</math>, given the observation HH, is 1. Two heads in a row does not prove that the coin always comes up heads, because two heads in a row is possible for any <math>p_\text{H} > 0</math>.
 
The likelihood function is not a [[probability density function]]. The integral of a likelihood function is not in general 1.  In this example, the integral of the likelihood over the interval [0, 1] in <math>p_\text{H}</math> is 1/3, demonstrating that the likelihood function cannot be interpreted as a probability density function for <math>p_\text{H}</math>.
 
==Example 2==
{{Main|German tank problem}}
 
Consider a jar containing ''N'' lottery tickets numbered from 1 through ''N''. If you pick a ticket randomly then you get positive integer ''n'', with probability 1/''N'' if ''n''&nbsp;≤&nbsp;''N'' and with probability zero if ''n''&nbsp;>&nbsp;''N''. This can be written
 
:<math>P(n|N)= \frac{[n \le N]}{N}</math>
 
where the [[Iverson bracket]] [''n''&nbsp;≤&nbsp;''N''] is 1 when ''n''&nbsp;≤&nbsp;''N'' and 0 otherwise.
When considered a function of ''n'' for fixed ''N'' this is the probability distribution, but when considered a function of ''N'' for fixed ''n'' this is a likelihood function. The [[maximum likelihood]] estimate for ''N'' is ''N''<sub>0</sub>&nbsp;=&nbsp;''n'' (by contrast, the [[Bias_of_an_estimator#Maximum_of_a_discrete_uniform_distribution|unbiased estimate]] is 2''n''&nbsp;&minus;&nbsp;1).
 
This likelihood function is not a probability distribution, because the total
 
:<math>\sum_{N=1}^\infty P(n|N) = \sum_{N} \frac{[N \ge n]}{N} = \sum_{N=n}^\infty \frac{1}{N}</math>
 
is a [[divergent series]].
 
Suppose, however, that you pick ''two'' tickets rather than ''one''.
 
The probability of the outcome {''n''<sub>1</sub>,&nbsp;''n''<sub>2</sub>}, where ''n''<sub>1</sub>&nbsp;<&nbsp;''n''<sub>2</sub>, is
 
:<math>P(\{n_1,n_2\}|N)= \frac{[n_2 \le N]}{\binom N 2} .</math>
 
When considered a function of ''N'' for fixed ''n''<sub>2</sub>, this is a likelihood function. The [[maximum likelihood]] estimate for ''N'' is ''N''<sub>0</sub>&nbsp;=&nbsp;''n''<sub>2</sub>.
 
This time the total
 
:<math>\sum_{N=1}^\infty P(\{n_1,n_2\}|N)
= \sum_{N} \frac{[N\ge n_2]}{\binom N 2}
=\frac 2 {n_2-1}  </math>
 
is a convergent series, and so this likelihood function can be normalized into a probability distribution.
 
If you pick 3 or more tickets, the likelihood function has a well defined [[mean value]], which is larger than the maximum likelihood estimate. If you pick 4 or more tickets, the likelihood function has a well defined  [[standard deviation]] too.
 
==Relative likelihood==
 
===Relative likelihood function===
Suppose that the [[maximum likelihood]] estimate for ''&theta;'' is <math>\hat \theta</math>.  Relative plausibilities of other ''&theta;'' values may be found by comparing the likelihood of those other values with the likelihood of <math>\hat \theta</math>.  The '''relative likelihood''' of ''&theta;'' is defined<ref name='Kalbfleisch'>Kalbfleisch J.G. (1985) ''Probability and Statistical Inference'', Springer (&sect;9.3.)</ref><ref name='Sprott'>Sprott D.A. (2000) ''Statistical Inference in Science'', Springer (chap.2)</ref> as <math>\mathcal{L}(\theta | x)/\mathcal{L}(\hat \theta | x).</math>
 
A 10% likelihood region for ''&theta;'' is
:<math>\{\theta : \mathcal{L}(\theta | x)/\mathcal{L}(\hat \theta | x) \ge 0.10\},</math>
and more generally, a ''p''% '''likelihood region''' for ''&theta;'' is defined<ref name='Kalbfleisch'/><ref name='Sprott'/> to be
:<math>\{\theta : \mathcal{L}(\theta | x)/\mathcal{L}(\hat \theta | x) \ge p/100 \}.</math>
If ''&theta;'' is a single real parameter, a ''p''% likelihood region will typically comprise an interval of real values.  In that case, the region is called a '''likelihood interval'''.<ref name='Kalbfleisch'/><ref name='Sprott'/><ref name=Hudson>{{Cite journal
| last1 = Hudson | first1 = D. J.
| title = Interval Estimation from the Likelihood Function
| journal = [[Journal of the Royal Statistical Society, Series B]]
| volume = 33
| issue = 2
| pages = 256–262
| doi = 
| year = 1971
| pmid = 
| pmc =
}}</ref>
 
Likelihood intervals can be compared to [[confidence interval]]s.  If ''&theta;'' is a single real parameter, then under certain conditions, a 14.7% likelihood interval for ''&theta;'' will be the same as a 95% confidence interval.<ref name='Kalbfleisch'/> In a slightly different formulation suited to the use of log-likelihoods, the ''e''<sup>&minus;2</sup> likelihood interval is the same as the 0.954 confidence interval (under certain conditions).<ref name=Hudson/>
 
The idea of basing an [[interval estimate]] on the relative likelihood goes back to [[Sir Ronald Fisher|Fisher]] in 1956 and has been used by many authors since then.<ref name=Hudson/> If a likelihood interval is specifically to be interpreted as a [[confidence interval]], then this idea is immediately related to the [[likelihood ratio test]] which can be used to define appropriate intervals for parameters. This approach can be used to define the critical points for the likelihood ratio statistic to achieve the required coverage level for a confidence interval. However a likelihood interval can be used as such, having been determined in a well-defined way, without claiming any particular [[coverage probability]].
 
===Relative likelihood of models===
The definition of relative likelihood can also be generalized to compare different (fitted) statistical models.  This generalization is based on [[Akaike information criterion]], or more usually, [[Akaike Information Criterion#AICc|AICc]] (Akaike Information Criterion with correction).  Suppose that, for some dataset, we have two statistical models, ''M''<sub>1</sub> and ''M''<sub>2</sub>, with fixed parameters.  Also suppose that AICc(''M''<sub>1</sub>) &le; AICc(''M''<sub>2</sub>).  Then the '''relative likelihood''' of ''M''<sub>2</sub> with respect to ''M''<sub>1</sub> is defined<ref>Burnham K. P. & Anderson D.R. (2002), ''Model Selection and Multimodel Inference'', &sect;2.8 (Springer).</ref> to be
:exp((AICc(''M''<sub>1</sub>)&minus;AICc(''M''<sub>2</sub>))/2)
 
To see that this is a generalization of the earlier definition, suppose that we have some model ''M'' with a (possibly multivariate) parameter ''&theta;''.  Then for any ''&theta;'', set ''M''<sub>2</sub> = ''M''(''&theta;''), and also set ''M''<sub>1</sub> = ''M''(<math>\hat\theta</math>).  The general definition now gives the same result as the earlier definition.
 
==Likelihoods that eliminate nuisance parameters==
In many cases, the likelihood is a function of more than one parameter but interest focuses on the estimation of only one, or at most a few of them, with the others being considered as [[nuisance parameter]]s. Several alternative approaches have been developed to eliminate such nuisance parameters so that a likelihood can be written as a function of only the [[Nuisance parameter|parameter (or parameters) of interest]]; the main approaches being marginal, conditional and profile likelihoods.<ref>
{{cite book
| title=In All Likelihood: Statistical Modelling and Inference Using Likelihood
| first=Yudi | last=Pawitan | year=2001| publisher=Oxford University Press|isbn=0-19-850765-8
}}</ref><ref>
{{cite web | author = Wen Hsiang Wei
| url= http://web.thu.edu.tw/wenwei/www/glmpdfmargin.htm
| title = Generalized linear model course notes | pages = Chapter 5
| publisher = Tung Hai University, Taichung, Taiwan | accessdate = 2007-01-23 }}</ref>
 
These approaches are useful because standard likelihood methods can become unreliable or fail entirely when there are many nuisance parameters or when the nuisance parameters are high-dimensional.  This is particularly true when the nuisance parameters can be considered to be "missing data"; they represent a non-negligible fraction of the number of observations and this fraction does not decrease when the sample size increases. Often these approaches can be used to derive closed-form formulae for statistical tests when direct use of maximum likelihood requires iterative numerical methods.  These approaches find application in some specialized topics such as [[sequential analysis]].
 
===Conditional likelihood===
Sometimes it is possible to find a [[sufficient statistic]] for the nuisance parameters, and conditioning on this statistic results in a likelihood which does not depend on the nuisance parameters.
 
One example occurs in 2×2 tables, where conditioning on all four marginal totals leads to a conditional likelihood based on the non-central [[hypergeometric distribution]]. This form of conditioning is also the basis for [[Fisher's exact test]].
 
===Marginal likelihood===
{{Main|Marginal likelihood}}
<!-- needs expansion  ~~~~ -->
Sometimes we can remove the nuisance parameters by considering a likelihood based on only part of the information in the data, for example by using the set of ranks rather than the numerical values. Another example occurs in linear [[mixed model]]s, where considering a likelihood for the residuals only after fitting the fixed effects leads to [[residual maximum likelihood]] estimation of the variance components.
 
===Profile likelihood===
<!-- 1st 2 paras based on material previously headed "Concentrated likelihood"  ~~~~~ -->
It is often possible to write some parameters as functions of other parameters, thereby reducing the number of independent parameters.
(The function is the parameter value which maximizes the likelihood given the value of the other parameters.)
This procedure is called concentration of the parameters and results in the concentrated likelihood function, also occasionally known as the maximized likelihood function, but most often called the profile likelihood function.
<!--
Suggestions for expansion: an example of concentration [added below, on august 27, 2005]; explanation on usage in maximum likelihood in optimization -->
 
For example, consider a [[regression analysis]] model with [[normal distribution|normally distributed]] [[errors and residuals in statistics|errors]]. The most likely value of the error [[variance]] is the variance of the [[errors and residuals in statistics|residuals]]. The residuals depend on all other parameters. Hence the variance parameter can be written as a function of the other parameters.
 
Unlike conditional and marginal likelihoods, profile likelihood methods can always be used, even when the profile likelihood cannot be written down explicitly. However, the profile likelihood is not a true likelihood, as it is not based directly on a probability distribution, and this leads to some less satisfactory properties.  Attempts have been made to improve this, resulting in modified profile likelihood.
 
The idea of profile likelihood can also be used to compute [[confidence interval]]s that often have better small-sample properties than those based on asymptotic [[Standard error (statistics)|standard errors]] calculated from the full likelihood. In the case of parameter estimation in partially observed systems, the profile likelihood can be also used for [[identifiability]] analysis.<ref>
{{cite journal
|last=Raue |first=A
|title=Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood
|url=http://bioinformatics.oxfordjournals.org/cgi/content/abstract/btp358?ijkey=iYp4jPP50F5vdX0&keytype=ref
|journal=Bioinformatics
|year=2009
|doi=10.1093/bioinformatics/btp358
|pmid=19505944
|last2=Kreutz
|first2=C
|last3=Maiwald
|first3=T
|last4=Bachmann
|first4=J
|last5=Schilling
|first5=M
|last6=Klingmüller
|first6=U
|last7=Timmer
|first7=J
|volume=25
|issue=15
|pages=1923–9
}}</ref>
Results from profile likelihood analysis can be incorporated in [[uncertainty analysis]] of model predictions.<ref>
{{cite journal
|last=Vanlier |first=J
|title=An integrated strategy for prediction uncertainty analysis
|url=http://bioinformatics.oxfordjournals.org/content/28/8/1130.long
|journal=Bioinformatics
|year=2012
|doi=10.1093/bioinformatics/bts088
|pmid=22355081
|last2=Tiemann
|first2=C
|last3=Hilbers
|first3=P
|last4=van Riel
|first4=N
|volume=28
|issue=8
|pages=1130–5
}}</ref>
An implementation is available in the MATLAB Toolbox [[PottersWheel]].
 
===Partial likelihood===
A partial likelihood is a factor component of the likelihood function that isolates the parameters of interest.<ref>
{{cite journal
|last=Cox |first=D. R. |authorlink=David Cox (statistician)
|title=Partial likelihood
|journal=[[Biometrika]]
|year=1975 |volume=62 |issue=2 |pages=269&ndash;276
|doi=10.1093/biomet/62.2.269 |mr=0400509
}}</ref> It is a key component of the [[proportional hazards model]].
 
==Historical remarks==
In English, "likelihood" has been distinguished as being related to, but weaker than, "probability" since its earliest uses. The comparison of hypotheses by evaluating likelihoods has been used for centuries, for example by [[John Milton]] in [[Aeropagitica]] (1644): "when greatest likelihoods are brought that such things are truly and really in those persons to whom they are ascribed".
 
In the Netherlands [[Christiaan Huygens]] used the concept of likelihood in his book "Van rekeningh in spelen van geluck" ("On Reasoning in Games of Chance") in 1657.
 
In Danish, "likelihood" was used by [[Thorvald N. Thiele]] in 1889.<ref>{{cite book |title=A History of Mathematical Statistics from 1750 to 1930 |author=[[Anders Hald]]|year=1998 |publisher=Wiley |location=New York |isbn=0-471-17912-4}}</ref><ref>[[Steffen L. Lauritzen]], [http://www.stats.ox.ac.uk/~steffen/papers/isi99.ps  ''Aspects of T. N. Thiele’s Contributions to Statistics'']. ''Bulletin of the [[International Statistical Institute]]'', 58, 27–30, 1999.</ref><ref>
{{cite book|author=[[Steffen L. Lauritzen]]|title=Thiele: Pioneer in Statistics|publisher=[Oxford University Press]|year=2002|pages=288|isbn=978-0-19-850972-1}}</ref>
 
In English, "likelihood" appears in many writings by [[Charles Sanders Peirce]], where [[Statistical model|model]]-based inference (usually [[abductive reasoning|abduction]] but sometimes including [[inductive reasoning|induction]]) is distinguished from statistical procedures based on [[objective]]{{Disambiguation needed|date=January 2012}} [[randomization]]. Peirce's preference for randomization-based inference is discussed in "[[Charles Sanders Peirce bibliography#illus|Illustrations of the Logic of Science]]" (1877–1878) and "[[Charles Sanders Peirce bibliography#SIL|A Theory of Probable Inference]]" (1883)".  <blockquote>
"probabilities that are strictly objective and at the same time very great, although they can never be absolutely conclusive, ought nevertheless to influence our preference for one hypothesis over another; but slight probabilities, even if objective, are not worth consideration; and merely subjective likelihoods should be disregarded altogether. For they are merely expressions of our preconceived notions" (7.227 in his ''[[Charles Sanders Peirce bibliography#CP|Collected Papers]]'').
</blockquote>
<blockquote>
"But experience must be our chart in economical navigation; and experience shows that likelihoods are treacherous guides. Nothing has caused so much waste of time and means, in all sorts of researchers, as inquirers' becoming so wedded to certain likelihoods as to forget all the other factors of the economy of research; so that, unless it be very solidly grounded, likelihood is far better disregarded, or nearly so; and even when it seems solidly grounded, it should be proceeded upon with a cautious tread, with an eye to other considerations, and recollection of the disasters caused." (''[[Charles Sanders Peirce bibliography#EP|Essential Peirce]]'', volume 2, pages 108–109)
</blockquote>
Like Thiele, Peirce considers the likelihood for a binomial distribution. Peirce uses the [[log odds|logarithm of the odds-ratio]] throughout his career. Peirce's propensity for using the [[log odds]] is discussed by [[Stephen Stigler]].{{Citation needed|date=November 2010}}
 
In Great Britain, "likelihood" was popularized in mathematical statistics by [[R.A. Fisher]] in 1922:<ref name=Fisher1922>{{cite journal
| last=Fisher | first=R.A. |authorlink=Ronald Fisher
| journal= Philosophical Transactions of the Royal Society A
| title=On the mathematical foundations of theoretical statistics
| volume=222
| issue=594–604 | year=1922 | pages=309–368
| url=http://digital.library.adelaide.edu.au/dspace/handle/2440/15172
| jstor=91208 | jfm = 48.1280.02 |doi=10.1098/rsta.1922.0009
}}</ref> "On the mathematical foundations of theoretical statistics". In that paper, Fisher also uses the term "[[method of maximum likelihood]]". Fisher argues against [[inverse probability]] as a basis for statistical inferences, and instead proposes inferences based on likelihood functions. Fisher's use of "likelihood" fixed the terminology that is used by statisticians throughout the world.
 
== See also ==
* [[Bayes factor]]
* [[Bayesian inference]]
* [[Conditional probability]]
* [[Likelihood principle]]
* [[Maximum likelihood]]
* [[Likelihood-ratio test]]
* [[Principle of maximum entropy]]
* [[Conditional entropy]]
* [[Score (statistics)]]
 
==Notes==
{{Reflist}}
 
==References==
* {{Cite journal |doi=10.1214/aos/1176343457 |title=[[Francis Ysidro Edgeworth|F. Y. Edgeworth]] and [[R. A. Fisher]] on the Efficiency of Maximum Likelihood Estimation | author=[[John W. Pratt]]| journal=The Annals of Statistics| volume=4| issue=3 |date=May 1976|pages=501&ndash;514 }} | jstor = 2958222
* {{Cite journal |doi=10.2307/2344804 |title=[[Francis Ysidro Edgeworth]], Statistician|author=Stephen M. Stigler|authorlink=Stephen Stigler|journal= [[Journal of the Royal Statistical Society, Series A]] | volume=141 |issue= 3 |year= 1978 | pages =287&ndash;322 |jstor=2344804 }} | jstor = 2344804
* {{Cite book|author=Stephen M. Stigler|authorlink=Stephen Stigler|title=The History of Statistics: The Measurement of Uncertainty before 1900| isbn=0-674-40340-1|publisher=Harvard University Press}}
* {{Cite book|author=Stephen M. Stigler|authorlink=Stephen Stigler|title=Statistics on the Table: The History of Statistical Concepts and Methods| isbn=0-674-83601-4|publisher=Harvard University Press}}
* {{Cite journal | title=On the History of Maximum Likelihood in Relation to Inverse Probability and Least Squares| author= Anders Hald |authorlink=Anders Hald
|journal=Statistical Science|volume= 14| issue=2 |year=1999 | pages =214&ndash;222 }} | jstor = 2676741
* {{Cite book| author=Hald, A. |authorlink=Anders Hald|year=1998| title=A History of Mathematical Statistics from 1750 to 1930| publisher=Wiley| location=New York| isbn=0-471-17912-4}}
 
==External links==
{{Wiktionary|likelihood}}
* [http://planetmath.org/encyclopedia/LikelihoodFunction.html Likelihood function at Planetmath]
 
{{DEFAULTSORT:Likelihood Function}}
[[Category:Estimation theory]]
[[Category:Bayesian statistics]]

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